Description
PDCD1 Antibody / PD-1 / PD1 | V7999SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: NAT105
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: FACS, IF, IHC-P
Buffer: N/A
Limitation: This PD1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
Immunogen: Human YT cells (NK-like leukemia cells) were used as the immunogen for the PD1 antibody.
Storage: Store the PD1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).
