Description
PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target)(PDL1/2743), CF405S conjugate, 0.1mg/mL Antibody | BNC042743-100| Gentaur Distribution US, UK & Europe
Summary.: PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .
Conjugate: CF405S.
Storage Buffer: PBS, 0.1% BSA, 0.05% azide.
Storage Temperature: 2°C to 8°C.
Application: Flow (verified)|IF (verified).
Stability: Stable at room temperature or 37°C (98°F) for 7 days.
