PD-L1 Antibody / B7-H1 / CD274 | V7822SAF-100UG

PD-L1 Antibody / B7-H1 / CD274 | V7822SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: PDL1/2742

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: ELISA

Buffer: N/A

Limitation: This PD-L1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

Immunogen: A portion of amino acids 39-191 from the human protein was used as the immunogen for this PD-L1 antibody.

Storage: Store the PD-L1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).