Description
PD-L1 Antibody / B7-H1 / CD274 | V3955BTN | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Biotin Conjugate
Clone: PDL1/2746
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human
Application: FACS, IF, WB, IHC-P
Buffer: N/A
Limitation: This PD-L1 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
Immunogen: A portion of amino acids 39-191 from the human protein was used as the immunogen for the PD-L1 antibody.
Storage: Store the PD-L1 antibody at 2-8oC (up to one month) or aliquot and store at -20 °C (longer term).
