PCNA Polyclonal Antibody | E-AB-40056

PCNA Polyclonal Antibody | E-AB-40056 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Tags and Cell Markers

Background: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.

Lead Time: 7~10 days

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant human Proliferating cell nuclear antigen protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification: Affinity purification

Dilution: WB 1:500-1:1000, IHC 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 29 kDa

Observed Molecular Weight: 34 kDa

Clonality: Polyclonal