Description
PCNA Polyclonal Antibody | E-AB-40056 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC
Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Tags and Cell Markers
Background: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Lead Time: 7~10 days
Concentration: 2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant human Proliferating cell nuclear antigen protein
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification: Affinity purification
Dilution: WB 1:500-1:1000, IHC 1:50-1:100
Conjugation: Unconjugated
Calculated Molecular Weight: 29 kDa
Observed Molecular Weight: 34 kDa
Clonality: Polyclonal
