Description
PCNA Polyclonal Antibody | E-AB-10010 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human , Mouse , Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC, ELISA
Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Tags and Cell Markers
Background: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Lead Time: 7~10 days
Concentration: 0.5 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant protein of human PCNA
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:50-1:200
Conjugation: Unconjugated
Calculated Molecular Weight: 29 kDa
Observed Molecular Weight: Refer to figures
Clonality: Polyclonal
