Description
PCNA Monoclonal Antibody | E-AB-22001 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Mouse
Isotype: IgG
Application: WB, IHC-p, IF
Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Tags and Cell Markers
Background: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Lead Time: 7~10 days
Concentration: 1 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic Peptide
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification: Protein A purification
Dilution: WB 1:5000-1:10000, IHC 1:100-1:300, IF 1:100-1:300
Conjugation: Unconjugated
Calculated Molecular Weight: 29 kDa
Observed Molecular Weight: 29 kDa
Clonality: Monoclonal
