PCK1 Polyclonal Antibody | E-AB-40269

PCK1 Polyclonal Antibody | E-AB-40269 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Application: IHC

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Background: This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Rat Phosphoenolpyruvate carboxykinase, cytosolic [GTP] protein

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Purification: Antigen Affinity Purification

Dilution: IHC 1:100-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: N/A

Observed Molecular Weight: N/A

Clonality: Polyclonal