Description
PBK Polyclonal Antibody | E-AB-40065 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC
Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signaling transduction
Background: PBK(PDZ-binding kinase) is also named as TOPK, CT84, Nori-3, SPK and belongs to the MAP kinase kinase subfamily. PBK may have a role in the regulation of cellular proliferation and progression of the cell cycle. It has a characteristic cdc2ycyclin B phosphorylation site(SyT-P-X-KyR) at its N terminus, which is conserved across species, and it is phosphorylated in a cell cycle-dependent manner at mitosis, and that this phosphorylation is required for its activation.
Lead Time: 7~10 days
Concentration: 2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Recombinant Human Lymphokine-activated killer T-cell-originated protein kinase protein
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification: Affinity purification
Dilution: WB 1:500-1:1000, IHC 1:50-1:100
Conjugation: Unconjugated
Calculated Molecular Weight: 36 kDa
Observed Molecular Weight: 40 kDa
Clonality: Polyclonal