PBK Polyclonal Antibody | E-AB-40065

PBK Polyclonal Antibody | E-AB-40065 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signaling transduction

Background: PBK(PDZ-binding kinase) is also named as TOPK, CT84, Nori-3, SPK and belongs to the MAP kinase kinase subfamily. PBK may have a role in the regulation of cellular proliferation and progression of the cell cycle. It has a characteristic cdc2ycyclin B phosphorylation site(SyT-P-X-KyR) at its N terminus, which is conserved across species, and it is phosphorylated in a cell cycle-dependent manner at mitosis, and that this phosphorylation is required for its activation.

Lead Time: 7~10 days

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant Human Lymphokine-activated killer T-cell-originated protein kinase protein

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification: Affinity purification

Dilution: WB 1:500-1:1000, IHC 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 36 kDa

Observed Molecular Weight: 40 kDa

Clonality: Polyclonal