Description
PARP1 Homogenous Assay Kit | 78438 | Gentaur US, UK & Europe Disrtribition
Category: PARP/Assay Kit
Application: • Screen for molecules that inhibit PARP1 activity.
Background: N/A
Description: The PARP1 Homogeneous Assay Kit is designed to measure PARP1 activity for screening and profiling applications. PARP1 is known to catalyze the NAD-dependent addition of poly(ADP-ribose) to histones. The key to the PARP1 Homogeneous Assay Kit is a highly specific antibody that recognizes PARylated substrate. With this kit, only three simple steps are required for PARP1 reactions. First, a sample containing PARP1 enzyme is incubated with biotinylated substrate and NAD for one hour. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.
Product Type: Assay Kit
Shippement Condition: -80°C
