PARP1 Antibody | RQ5291

PARP1 Antibody | RQ5291 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: ABCG-16

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human

Application: WB

Buffer: N/A

Limitation: This PARP1 antibody is available for research use only.

Purity: Affinity purified

Description: The PARP1 gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [RefSeq]

Immunogen: A synthetic peptide specific to human PARP1 (auto-modification/catalytic domain) was used as the immunogen for the PARP1 antibody.

Storage: Store the PARP1 antibody at -20 °C.