Description
PAK4 Antibody | F50893-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: IHC, WB, ELISA
Buffer: N/A
Limitation: This PAK4 antibody is available for research use only.
Purity: Purified
Description: PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.
Immunogen: A portion of amino acids 156-187 from the human protein was used as the immunogen for this PAK4 antibody.
Storage: Aliquot the PAK4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
