Description
Pak4 Antibody | F43855-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, FACS, ELISA
Buffer: N/A
Limitation: This Pak4 antibody is available for research use only.
Purity: Antigen affinity
Description: Pak4 activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2 (By similarity).
Immunogen: A portion of amino acids 187-216 from the mouse protein was used as the immunogen for this Pak4 antibody.
Storage: Aliquot the Pak4 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
