Description
PAFAH1B3 Polyclonal Antibody | E-AB-19183 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC, ELISA
Research Area: Cardiovascular, Metabolism, Neuroscience, Signal transduction
Background: This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.
Lead Time: 7~10 days
Concentration: 1.2 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Fusion protein of human PAFAH1B3
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification: Antigen affinity purification
Dilution: WB 1:1000-1:5000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Conjugation: Unconjugated
Calculated Molecular Weight: 26 kDa
Observed Molecular Weight: Refer to figures
Clonality: Polyclonal
