PACSIN2 Antibody | F53991-0.08ML

PACSIN2 Antibody | F53991-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, IHC-P, IF

Buffer: N/A

Limitation: This PACSIN2 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Protein kinase C and casein kinase substrate in neurons protein 2 is a lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.

Immunogen: A portion of amino acids 342-371 from the human protein was used as the immunogen for the PACSIN2 antibody.

Storage: Aliquot the PACSIN2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.