Description
PACSIN2 Antibody | F53980-0.05ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 1735CT116.76.60
Host Animal: Mouse
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB
Buffer: N/A
Limitation: This PACSIN2 antibody is available for research use only.
Purity: Protein G affinity chromatography
Description: Protein kinase C and casein kinase substrate in neurons protein 2 is a lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
Immunogen: A partial recombinant protein corresponding to amino acids 250-486 from the human protein was used as the immunogen for the PACSIN2 antibody.
Storage: Aliquot the PACSIN2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
