Description
P2X4 Antibody | R31717 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat, Monkey
Application: WB
Buffer: N/A
Limitation: This P2X4 antibody is available for research use only.
Purity: Antigen affinity
Description: Purinoceptor P2X4, also called P2X4R is a protein that in humans is encoded by the P2RX4 gene. This gene belongs to the family of purinoceptors for ATP. P2RX4 is a receptor for ATP that acts as a ligand-gated ion channel. P2X4 in hyperactive microglia is necessary for tactile allodynia after nerve injury and is sufficient to produce tactile allodynia in normal animals. P2X receptors have beeb implicated in the regulation of cardiac function, ATP-mediated cell death, synaptic strengthening, and activating of the inflammasome in response to injury.
Immunogen: Human partial recombinant protein (AA 262-388) was used as the immunogen for this P2X4 antibody.
Storage: The P2X4 antibody can be stored at 4oC to -20 °C. After reconstitution, aliquot and store at -20 °C. Avoid repeated freeze/thaws.