p27Kip1 Antibody | F52107-0.4ML

p27Kip1 Antibody | F52107-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Mouse

Application: WB, ELISA

Buffer: N/A

Limitation: This p27Kip1 antibody is available for research use only.

Purity: Antigen affinity

Description: Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E-and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of cyclin D-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Immunogen: A portion of amino acids 175-197 from the mouse protein was used as the immunogen for this p27Kip1 antibody.

Storage: Aliquot the p27Kip1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.