p27 / KIP1(DCS-72.F6 + KIP1/769 (SX53G8)), Biotin conjugate, 0.1mg/mL Antibody | BNCB1237-100

p27 / KIP1(DCS-72.F6 + KIP1/769 (SX53G8)), Biotin conjugate, 0.1mg/mL Antibody | BNCB1237-100| Gentaur Distribution US, UK & Europe

Summary.: Recognizes a 27 kDa protein, identified as the p27/Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27/Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF-beta-induced G1 arrest. p27/Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27/Kip1 and is excellent for staining of formalin-fixed tissues. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .

Conjugate: Biotin.

Storage Buffer: PBS, 0.1% BSA, 0.05% azide.

Storage Temperature: 2°C to 8°C.

Application: IHC, FFPE (verified).

Stability: Stable at room temperature or 37°C (98°F) for 7 days.