Description
p19-INK4d Antibody / CDKN2D | F55034-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: FACS, IHC-P, WB
Buffer: N/A
Limitation: This CDKN2D antibody is available for research use only.
Purity: Antigen affinity purified
Description: p19 / Cyclin-dependent kinase 4 inhibitor D is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis.
Immunogen: A portion of amino acids 15-43 from the human protein was used as the immunogen for the CDKN2D antibody.
Storage: Aliquot the CDKN2D antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
