p120 Catenin Antibody / CTNND1 / Catenin delta 1 | V9324-20UG

p120 Catenin Antibody / CTNND1 / Catenin delta 1 | V9324-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: CTNND1/4501

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This Delta 1 Catenin antibody is available for research use only.

Purity: Protein A/G affinity

Description: Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin (delta-1-catenin) binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, delta-1-catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins.

Immunogen: A portion of amino acids 138-276 was used as the immunogen for the Delta 1 Catenin antibody.

Storage: Aliquot the Delta 1 Catenin antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.