p120 Catenin Antibody / CTNND1 / Catenin delta 1 | V9163SAF-100UG

p120 Catenin Antibody / CTNND1 / Catenin delta 1 | V9163SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: CTNND1/4383R

Host: Rabbit

Clonality: Recombinant Rabbit Monoclonal

Isotype: Rabbit IgG

Species Reactivity: Human

Application: IHC-P

Application Details: Immunohistochemistry (FFPE): 2-4ug/ml

Application Note: Optimal dilution of the recombinant Delta 1 Catenin antibody should be determined by the researcher.

Purity: Protein A/G affinity

Description: Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin (delta-1-catenin) binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, delta-1-catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins.

Immunogen: A portion of amino acids 900-1,000 was used as the immunogen for the recombinant Delta 1 Catenin antibody.

Storage: Aliquot the recombinant Delta 1 Catenin antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.

Localization: Cell Surface, Cytoplasm