Description
p120 Catenin Antibody / CTNND1 / Catenin delta 1 | V9163SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: CTNND1/4383R
Host: Rabbit
Clonality: Recombinant Rabbit Monoclonal
Isotype: Rabbit IgG
Species Reactivity: Human
Application: IHC-P
Application Details: Immunohistochemistry (FFPE): 2-4ug/ml
Application Note: Optimal dilution of the recombinant Delta 1 Catenin antibody should be determined by the researcher.
Purity: Protein A/G affinity
Description: Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin (delta-1-catenin) binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, delta-1-catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins.
Immunogen: A portion of amino acids 900-1,000 was used as the immunogen for the recombinant Delta 1 Catenin antibody.
Storage: Aliquot the recombinant Delta 1 Catenin antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
Localization: Cell Surface, Cytoplasm
