P-Cadherin Antibody / CDH3 | V3397-20UG

P-Cadherin Antibody / CDH3 | V3397-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: 6A9

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, WB

Buffer: N/A

Limitation: This P-Cadherin antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: Recognizes a protein of 116kDa, identified as P-Cadherin, or Cadherin 3 or CDH3. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.

Immunogen: Membrane from trypsinized A431 cells was used as the immunogen for this P-Cadherin antibody.

Storage: Store the P-Cadherin antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).