Ornithine Decarboxylase Antibody / ODC1 | V2215-20UG

Ornithine Decarboxylase Antibody / ODC1 | V2215-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Format: Purified

Clone: ODC1/485

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse, Rat

Application: FACS, IF, WB, IHC-P

Buffer: N/A

Limitation: This ODC-1 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This antibody recognizes a 53kDa protein, identified as the Ornithine Decarboxylase. ODC-1 is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC-1 mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. Activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Immunogen: Recombinant human ODC-1 protein was used as the immunogen for this antibody.

Storage: Store the ODC-1 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).