Description
Oct4 Antibody / POU5F1 | V4000SAF-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free
Format: Purified
Clone: OCT4/6847R
Host: Rabbit
Clonality: Recombinant Rabbit Monoclonal
Isotype: Rabbit IgG, kappa
Species Reactivity: Human
Application: IHC-P
Application Details: Immunohistochemistry (FFPE): 1-2ug/ml
Application Note: Optimal dilution of the POU5F1 antibody should be determined by the researcher.
Purity: Protein A/G affinity
Description: OCT4/POU5F1 is a member of the POU family of transcription factors, involved in the regulation of pluripotency during normal development and is detectable in embryonic stem and germ cells. It is a key regulator of self-renewal in embryonic stem cells; its expression is potentially correlated with tumorigenesis and can affect tumor recurrence or resistance to therapies. OCT4/POU5F1 is expressed in undifferentiated pluripotent cells, germ cells in ovary and testis.
Immunogen: Recombinant fragment from the human protein was used as the immunogen for the POU5F1 antibody.
Storage: Aliquot the POU5F1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
Localization: Nucleus
