Description
Oct-1 Antibody (POU2F1) | R31730 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC-P
Buffer: N/A
Limitation: This Oct-1 antibody is available for research use only.
Purity: Antigen affinity
Description: POU domain class 2 transcription factor 1, also known as OTF1 or Oct-1, is a protein that in humans is encoded by the POU2F1 gene. The transcription factor was among the first identified members of the POU transcription factor family. It has been found that the Oct-1 dimer formed on the palindromic OCT factor recognition element, or PORE (ATTTGAAATGCAAAT), could recruit the transcriptional coactivator OBF1, whereas dimers formed on the consensus MORE (more PORE) (ATGCATATGCAT) or on MOREs from immunoglobulin heavy chain promoters (AT[G/A][C/A]ATATGCAA) failed to interact. POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA.
Immunogen: Human partial recombinant protein (AA 11-240) was used as the immunogen for this Oct-1 antibody.
Storage: After reconstitution, the Oct-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
