NUDT15 Antibody | F54345-0.08ML

NUDT15 Antibody | F54345-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: FACS, IHC-P, WB

Buffer: N/A

Limitation: This NUDT15 antibody is available for research use only.

Purity: Antigen affinity purified

Description: Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.

Immunogen: A portion of amino acids 89-118 from the human protein was used as the immunogen for the NUDT15 antibody.

Storage: Aliquot the NUDT15 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.