Description
NUDT15 Antibody | F54345-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: FACS, IHC-P, WB
Buffer: N/A
Limitation: This NUDT15 antibody is available for research use only.
Purity: Antigen affinity purified
Description: Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.
Immunogen: A portion of amino acids 89-118 from the human protein was used as the immunogen for the NUDT15 antibody.
Storage: Aliquot the NUDT15 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
