Nucleophosmin Antibody (Npm1) | F48247-0.08ML

Nucleophosmin Antibody (Npm1) | F48247-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC, FACS, IF, WB, ELISA

Buffer: N/A

Limitation: This NPM1 antibody is available for research use only.

Purity: Purified

Description: Nucleophosmin/NPM1 is a ubiquitously expressed nucleolar protein that shuttles between the nucleus and cytoplasm. It is implicated in multiple functions, including ribosomal protein assembly and transport, control of centrosome duplication, and regulation of the tumor suppressor ARF. NPM1 mutations that relocalize NPM1 from the nucleus into the cytoplasm are associated with development of acute myeloid leukemia.

Immunogen: A portion of amino acids 7-33 from the human protein was used as the immunogen for this NPM1 antibody.

Storage: Aliquot the NPM1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.