NRAS Antibody | F50734-0.4ML

NRAS Antibody | F50734-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IHC, FACS, WB, ELISA

Buffer: N/A

Limitation: This NRAS antibody is available for research use only.

Purity: Purified

Description: NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).

Immunogen: A portion of amino acids 147-179 from the human protein was used as the immunogen for this NRAS antibody.

Storage: Aliquot the NRAS antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.