Description
NRAS Antibody | F50733-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, FACS, IF, ELISA
Buffer: N/A
Limitation: This NRAS antibody is available for research use only.
Purity: Purified
Description: NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).
Immunogen: A portion of amino acids 72-101 from the human protein was used as the immunogen for this NRAS antibody.
Storage: Aliquot the NRAS antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
