NR1I2 Antibody / PXR | F54461-0.08ML

NR1I2 Antibody / PXR | F54461-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: IF, FACS, IHC-P, WB

Buffer: N/A

Limitation: This PXR antibody is available for research use only.

Purity: Antigen affinity purified

Description: NR1I2/PXR belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. This protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin.

Immunogen: A portion of amino acids 100-127 from the human protein was used as the immunogen for the PXR antibody.

Storage: Aliquot the PXR antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.