Description
NQO1 Antibody | N1103-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: 1X PBS, pH 7.4
Limitation: This NQO1 antibody is available for research use only.
Purity: Protein A affinity chromatography
Description: NAD(P)H:quinone oxidoreductase is an enzyme that catalyzes the two-electron reduction of quinones to hydroquinones, resulting in the activation or deactivation of the hydroquinone. Increased expression of NQO1 is seen in tumors of the breast, liver and colon and NSCLC (non-small cell lung cancer), suggesting a role in tumor development and possibly treatment. NQO1 has also been linked to Alzheimer's disease, found to be upregulated in response to the oxidative stress of the AD process.
Immunogen: A recombinant protein fragment from the C-terminal region of human NQO1 was used as the immunogen for this antibody.
Storage: Aliquot and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
