Description
NPM1 Polyclonal Antibody | E-AB-40477 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB, IHC
Research Area: Cancer, Epigenetics and Nuclear Signaling
Background: Nucleophosmin (NPM1, B23) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs). The transport of proteins across the nuclear envelope is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. The 38 kDa nuclear protein nucleophosmin is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis.
Lead Time: Order now, ship in 3 day
Concentration: 1mg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: Recombinant Mouse Nucleophosmin protein
Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Purification: Antigen Affinity Purification
Dilution: WB 1:10000-1:20000 IHC 1:200-1:500
Conjugation: N/A
Calculated Molecular Weight: 32 kDa
Observed Molecular Weight: 37 kDa
Clonality: Polyclonal
