NPM1 Polyclonal Antibody | E-AB-40477

NPM1 Polyclonal Antibody | E-AB-40477 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cancer, Epigenetics and Nuclear Signaling

Background: Nucleophosmin (NPM1, B23) is a putative ribosome assembly factor with a high affinity for peptides containing nuclear localization signals (NLSs). The transport of proteins across the nuclear envelope is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Several cytosolic and nuclear proteins that are central to this process have been identified. The 38 kDa nuclear protein nucleophosmin is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis.

Lead Time: Order now, ship in 3 day

Concentration: 1mg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: Recombinant Mouse Nucleophosmin protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Purification: Antigen Affinity Purification

Dilution: WB 1:10000-1:20000 IHC 1:200-1:500

Conjugation: N/A

Calculated Molecular Weight: 32 kDa

Observed Molecular Weight: 37 kDa

Clonality: Polyclonal