Description
NLRP3 Antibody | F51203-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: WB, IHC, ELISA
Buffer: N/A
Limitation: This NLRP3 antibody is available for research use only.
Purity: Antigen affinity
Description: NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.
Immunogen: A portion of amino acids 65-91 from the human protein was used as the immunogen for this NLRP3 antibody.
Storage: Aliquot the NLRP3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
