NLRP3 Antibody | F51203-0.08ML

NLRP3 Antibody | F51203-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS pH 7.4 with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, ELISA

Buffer: N/A

Limitation: This NLRP3 antibody is available for research use only.

Purity: Antigen affinity

Description: NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.

Immunogen: A portion of amino acids 65-91 from the human protein was used as the immunogen for this NLRP3 antibody.

Storage: Aliquot the NLRP3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.