NLRP12 Polyclonal Antibody | E-AB-66298

NLRP12 Polyclonal Antibody | E-AB-66298 | Gentaur US, UK & Europe Disrtribition

Reactivity: Rat

Host: Rabbit

Isotype: IgG

Application: WB

Research Area: Cell Biology, Signal Transduction

Background: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human NLRP12 (NP_001264055.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000

Conjugation: Unconjugated

Calculated Molecular Weight: 31 kDa/101 kDa/107 kDa/113 kDa/114 kDa/120 kDa

Observed Molecular Weight: 120 kDa

Clonality: N/A