Description
Nkx3.1 Antibody | F47247-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Mouse
Application: WB, ELISA
Buffer: N/A
Limitation: This Nkx3.1 antibody is available for research use only.
Purity: Antigen affinity
Description: Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity). Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells. Play a role in the formation of minor salivary glands (particularly palatine and lingual glands). Essential for appropriate differentiation and secretory function of the bulbourethral gland.
Immunogen: A portion of amino acids 3-1 from the mouse protein was used as the immunogen for this Nkx3.1 antibody.
Storage: Aliquot the Nkx3.1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
