Description
NKIRAS1 Antibody | N1127-100UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: NRAS285
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: 1X PBS, pH 7.4
Limitation: This NKIRAS1 antibody is available for research use only.
Purity: Protein G purified antibody
Description: NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.
NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.
Immunogen: A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.
Storage: Aliquot the NKIRAS1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
