NKIRAS1 Antibody | N1127-100UG

NKIRAS1 Antibody | N1127-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: NRAS285

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse, Rat

Application: WB

Buffer: 1X PBS, pH 7.4

Limitation: This NKIRAS1 antibody is available for research use only.

Purity: Protein G purified antibody

Description: NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.

NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.

Immunogen: A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.

Storage: Aliquot the NKIRAS1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.