NK1.1 / CD161c / Klrb1c, Mouse(PK136), CF640R conjugate, 0.1mg/mL Antibody | BNC402010-100

NK1.1 / CD161c / Klrb1c, Mouse(PK136), CF640R conjugate, 0.1mg/mL Antibody | BNC402010-100| Gentaur Distribution US, UK & Europe

Summary.: NK1. 1 is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by theKlrb1c/NKR-P1Cgene. It is predominantly expressed as a disulfide-linked homodimer on NK cells however; it is also expressed on NK-T cells, a rare population of T lymphocytes. NK1. 1 is expressed in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allograftsin vivo. NK-1. 1 has also been shown to play a role in NK cell activation, IFN- production, and cytotoxic granule release. NK-1. 1 is commonly used as a mouse NK cell marker. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. .

Conjugate: CF640R.

Storage Buffer: PBS, 0.1% BSA, 0.05% azide.

Storage Temperature: 2°C to 8°C.

Application: Flow, surface (published)|Functional studies (published).

Stability: Stable at room temperature or 37°C (98°F) for 7 days.