NIK Antibody (Nck-interacting kinase) | F50948-0.08ML

NIK Antibody (Nck-interacting kinase) | F50948-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This NIK antibody is available for research use only.

Purity: Purified

Description: HGK/NIK, a member of the STE20 subfamily of Ser/Thr protein kinases, may play a role in the response to environmental stress and cytokines such as TNF-alpha. It appears to act upstream of the JUN N-terminal pathway. This protein is thought to interact with the SH3 domain of the adapter proteins Nck. HGK/NIK binds, via its CNH regulatory domain, to the N-terminal region of SPG3A. Expression appears to be ubiquitous, expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain, and isoform 4 is predominant in the liver, skeletal muscle and placenta.

Immunogen: A portion of amino acids 618-649 from the human protein was used as the immunogen for this NIK antibody.

Storage: Aliquot the NIK antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.