Description
NHERF1 Antibody / SLC9A3R1 | RQ4707 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: IIH-19
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human, Rat
Application: WB
Buffer: N/A
Limitation: This NHERF1 antibody is available for research use only.
Purity: Affinity purified
Description: The SLC9A3R1 gene encodes a sodium/hydrogen exchanger regulatory cofactor. Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (also called SLC9A3 regulator 1 and Ezrin-radixin-moesin-binding phosphoprotein 50) interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer. [RefSeq]
Immunogen: A synthetic peptide specific to human NHERF1 was used as the immunogen for the NHERF1 antibody.
Storage: Store the NHERF1 antibody at -20 °C.
