NGF Receptor Antibody / p75NTR / CD271 | V3892SAF-100UG

NGF Receptor Antibody / p75NTR / CD271 | V3892SAF-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 1 mg/ml in 1X PBS; BSA free, sodium azide free

Format: Purified

Clone: NGFR/1964

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This NGF Receptor antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.

Immunogen: A recombinant human partial protein corresponding to amino acids 281-421 was used as the immunogen for the NGF Receptor antibody.

Storage: Store the NGF Receptor antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).