NFATC1 Antibody | F43345-0.4ML

NFATC1 Antibody | F43345-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, ELISA

Buffer: N/A

Limitation: This NFATC1 antibody is available for research use only.

Purity: Antigen affinity

Description: The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Immunogen: A portion of amino acids 898-927 from the human protein was used as the immunogen for this NFATC1 antibody.

Storage: Aliquot the NFATC1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.