Description
NFAT Reporter (Luciferase) - THP-1 Cell Line | 78320 | Gentaur US, UK & Europe Disrtribition
Category: Cell Signaling/Cell Line
Application: • Monitor NFAT signaling pathway activity.
• Screen for compound activity on the NFAT signaling pathway.
Background: N/A
Description: The NFAT reporter (Luciferase)-THP-1 cell line is designed for monitoring the NFAT (nuclear factor of activated T-cells) signaling pathway in THP-1 cells by measuring luciferase activity. It contains a firefly luciferase gene driven by the NFAT response element located upstream of the minimal TATA promoter. Upon activation by NFAT activators such as Ionomycin, endogenous NFAT transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene.
Product Type: Cell Line
Shippement Condition: -80°C
