Neuroserpin Antibody / SERPINI1 | F54542-0.08ML

Neuroserpin Antibody / SERPINI1 | F54542-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, FACS, IF, IHC-P

Buffer: N/A

Limitation: This SERPINI1 antibody is available for research use only.

Purity: Antigen affinity purified

Description: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Immunogen: A portion of amino acids 19-45 from the human protein was used as the immunogen for the SERPINI1 antibody.

Storage: Aliquot the SERPINI1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.