Neurogenin 3 Antibody / NGN3 | F54290-0.4ML

Neurogenin 3 Antibody / NGN3 | F54290-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: WB, IHC-P, IF

Buffer: N/A

Limitation: This NGN3 antibody is available for research use only.

Purity: Antigen affinity purified

Description: Neurogenin-3 belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm. Neurogenin-3 also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. Defects in NEUROG3 are the cause of congenital malabsorptive diarrhea 4 (DIAR4). DIAR4 is an autosomal recessive disorder characterized by generalized malabsorption and a paucity of enteroendocrine cells.

Immunogen: A portion of amino acids 40-69 from the human protein were used as the immunogen for the NGN3 antibody.

Storage: Aliquot the NGN3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.