Description
Neurogenin 3 Antibody / NGN3 | F54290-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, IHC-P, IF
Buffer: N/A
Limitation: This NGN3 antibody is available for research use only.
Purity: Antigen affinity purified
Description: Neurogenin-3 belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm. Neurogenin-3 also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. Defects in NEUROG3 are the cause of congenital malabsorptive diarrhea 4 (DIAR4). DIAR4 is an autosomal recessive disorder characterized by generalized malabsorption and a paucity of enteroendocrine cells.
Immunogen: A portion of amino acids 40-69 from the human protein were used as the immunogen for the NGN3 antibody.
Storage: Aliquot the NGN3 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
