Neurofilament 200 Antibody (Heavy) | R30062

Neurofilament 200 Antibody (Heavy) | R30062 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS

Format: Ascites

Clone: N52

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, mouse, rat

Application: WB, IHC-P, IHC-F

Buffer: N/A

Limitation: This Neurofilament 200 antibody is available for research use only.

Purity: Ascites

Description: Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68kD (NFL), 125kD (NFM), and 200kD (NFH) on SDS-gel electrophoresis. It is thought that phosphorylation of NFH results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. Genomic clones for the largest human neurofilament protein were isolated, the intron/exon boundaries mapped and the entire protein-coding regions (exons) sequenced. Mutations in neurofilaments have been linked to some forms of Charcot-Marie-Tooth disease(CMT).

Immunogen: C-terminal segment of enzymatically dephosphorylated pig Neurofilament 200 was used as the immunogen for this Neurofilament 200 antibody.

Storage: Aliquot and store the Neurofilament 200 antibody at -20 °C. Avoid repeated freezing and thawing.