NeuroD1 Antibody | F47843-0.4ML

NeuroD1 Antibody | F47843-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB, ELISA

Buffer: N/A

Limitation: This NeuroD1 antibody is available for research use only.

Purity: Purified

Description: NeuroD1 is a transcriptional activator that acts as a differentiation factor during neurogenesis. It has been demonstrated to bind to the insulin gene E-box. Efficient DNA binding requires dimerization with another basic helix-loop-helix (bHLH) protein. Defects in NEUROD1 are a cause of maturity onset diabetes of the young type VI (MODY6). MODY6 is a form of non-insulin-dependent diabetes mellitus characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.

Immunogen: A portion of amino acids 318-348 from the human protein was used as the immunogen for this NeuroD1 antibody.

Storage: Aliquot the NeuroD1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.