Description
NEFH Polyclonal Antibody | E-AB-70063 | Gentaur US, UK & Europe Disrtribition
Reactivity: Mouse, Rat
Host: Rabbit
Isotype: IgG
Application: WB
Research Area: Cancer, Neuroscience, Signal Transduction
Background: NEFH, also named as KIAA0845 and NFH, Belongs to the intermediate filament family. It has an important function in mature axons that is not subserved by the two smaller NF proteins. Neurofilaments are the 10nm intermediate filaments found specifically in neurons. They are a major component of the cell's cytoskeleton, and provide support for normal axonal radial growth. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The names given to the three major neurofilament subunits are based upon the apparent molecular weight of the mammalian subunits on SDS-PAGE:NF-L, 65-68kd; NF-M, 145-160kd and NF-H, 200-220kd. This antibody recognize NEFH only.
Lead Time: 7~10 days
Concentration: 0.54 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse NF200
Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Purification: Affinity purification
Dilution: WB 1:500-1:2000
Conjugation: Unconjugated
Calculated Molecular Weight: 117 kDa
Observed Molecular Weight: 200 kDa
Clonality: Polyclonal
